Lbx1 expression and frog limb development.
Lbx1 expression and frog limb development.
复制标题
Lbx1 表达和青蛙肢体发育。
DOI：
10.1007/s00427-009-0314-8
复制
发表时间：
2009
影响因子：
2.4
通讯作者：
Elinson,RichardP
中科院分区：
文献类型：
--
作者：
Sabo,MichelleC;Nath,Kimberly;Elinson,RichardP
为了在青蛙中鉴定潜在的肢体肌细胞，我们从直接发育的青蛙Eleutherodactylus coqui中克隆了Lbx 1。与其他脊椎动物不同的是，EcLbx 1在所有躯干体节中都有表达，这与非洲爪蟾的胚胎相似。与鸡、小鼠和斑马鱼的胚胎一样，表达EcLbx 1的细胞随后在肢芽中被发现，这与这些细胞从体节迁移的情况一致。EcLbx1也在脊髓背侧表达，与其他脊椎动物一样。
In order to identify prospective limb muscle cells in a frog, we clonedLbx1from the direct developing frogEleutherodactylus coqui. Like in embryos of the frogXenopus laevisbut unlike in other vertebrates,EcLbx1is expressed in all trunk somites. Like in embryos of chick, mouse, and zebrafish, cells expressingEcLbx1are then found in limb buds, consistent with migration of those cells from somites. EcLbx1 is also expressed in the dorsal spinal cord as in other vertebrates.