ETIOLOGY OF OBESITY IN CHILDREN - STUDY OF 101 TWIN PAIRS
ETIOLOGY OF OBESITY IN CHILDREN - STUDY OF 101 TWIN PAIRS
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DOI：
10.1111/j.1651-2227.1976.tb04887.x
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发表时间：
1976-01-01
期刊：
影响因子：
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通讯作者：
BORJESON, M
中科院分区：
文献类型：
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作者：
BORJESON, M
本文对40例同卵双生子和61例异卵双生子进行了肥胖症的病因学研究。分析了遗传、早期营养和环境对学龄前儿童发育的重要性。通过比较同卵双胞胎和异卵双胞胎的配对内差异研究，遗传因素显然在肥胖的起源中起决定性作用。对不同类型双胞胎出生体重与皮下脂肪发育关系的分析表明，宫内营养在病因学上并不重要。在7岁时对不同类型的普通兄弟姐妹和双胞胎进行的比较不支持学前环境在病因学中具有重要性的观点。这种影响似乎主要是作为一种修正因素。
The etiology of obesity in children is studied with the aid of a material consisting of 40 monozygotic and 61 dizygotic twins. The importance of heredity, early nutrition and environment during preschool age is analyzed. Genetic factors, studied by comparison of intra-pair differences in monozygotic and dizygotic twins, apparently play a decisive role in the origin of obesity. Analysis of the relation between birth wt and later development of subcutaneous fat in different types of twins does not show that intrauterine nutrition is of etiological importance. The comparison at age 7 of groups of ordinary siblings and twins of different types does not support the idea that the pre-school environment is of importance in etiology. Such influence seems to act mainly as a modifying factor.