Intermittent Theta Burst Over M1 May Increase Peak Power of a Wingate Anaerobic Test and Prevent the Reduction of Voluntary Activation Measured with Transcranial Magnetic Stimulation
Intermittent Theta Burst Over M1 May Increase Peak Power of a Wingate Anaerobic Test and Prevent the Reduction of Voluntary Activation Measured with Transcranial Magnetic Stimulation
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DOI：
10.3389/fnbeh.2016.00150
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发表时间：
2016-07-19
影响因子：
3
通讯作者：
Gruber, Markus
中科院分区：
文献类型：
--
作者：
Giboin, Louis-Solal;Thumm, Patrick;Gruber, Markus
尽管重复经颅磁刺激（rTMS）的潜力，以改善运动神经元疾病患者的表现，其对运动性能增强健康受试者在特定的运动任务的影响仍然是未知的。我们假设，间歇性θ波爆发（iTBS）治疗后，温盖特无氧试验（WAnT）期间的表现将增加，运动后的脊髓上疲劳将低于对照治疗。10名受试者参加了两个随机实验，包括iTBS或对照治疗后5分钟的WAnT。在WAnT之前和之后，我们用TMS（VA（TMS））和股神经的外周神经刺激（VA（PNS））确定了右膝伸肌的自主激活（VA）。对WAnT结果进行T检验，对VA结果进行受试者内双向方差分析。与对照治疗相比，iTBS治疗增加了WAnT后的峰值功率和最大踏板节奏，并抑制了VA（TMS）的降低。未观察到与疲劳相关的行为变化（平均功率和疲劳指数）。这些结果首次表明，iTBS可以作为一种潜在的干预措施，以改善运动特定任务中的无氧性能。
Despite the potential of repetitive transcranial magnetic stimulation (rTMS) to improve performances in patients suffering from motor neuronal afflictions, its effect on motor performance enhancement in healthy subjects during a specific sport task is still unknown. We hypothesized that after an intermittent theta burst (iTBS) treatment, performance during the Wingate Anaerobic Test (WAnT) will increase and supraspinal fatigue following the exercise will be lower in comparison to a control treatment. Ten subjects participated in two randomized experiments consisting of a WAnT 5 min after either an iTBS or a control treatment. We determined voluntary activation (VA) of the right knee extensors with TMS (VA(TMS)) and with peripheral nerve stimulation (VA(PNS)) of the femoral nerve, before and after the WAnT. T-tests were applied to the WAnT results and a two way within subject ANOVA was applied to VA results. The iTBS treatment increased the peak power and the maximum pedalling cadence and suppressed the reduction of VA(TMS) following the WAnT compared to the control treatment. No behavioral changes related to fatigue (mean power and fatigue index) were observed. These results indicate for the first time that iTBS could be used as a potential intervention to improve anaerobic performance in a sport specific task.