Sodium sensitivity in normotensive human subjects.
Sodium sensitivity in normotensive human subjects.
复制标题
血压正常的人类受试者的钠敏感性。
DOI：
10.7326/0003-4819-98-5-758
复制
发表时间：
1983
影响因子：
39.2
通讯作者：
J. Z. Miller
中科院分区：
文献类型：
--
作者：
F. Luft;M. Weinberger;C. Grim;N. Fineberg;J. Z. Miller
令人信服的证据表明，高钠摄入在动脉高血压的发展和维持。然而，饮食钠限制仅在一小部分高血压患者中降低血压。对血压正常者的研究表明，黑人和老年人排泄钠负荷的效率低于体重和体表面积匹配的相同性别和种族的人。与白人相比，黑人对呋塞米容量收缩的反应表现出更大的尿钠排泄和血压下降。这些观察结果与黑人和老年人的内在肾异常一致，导致适度的体积扩张。这些变化可能会导致钠敏感性，并促进高钠摄入者高血压的发展和维持。
Compelling evidence implicates a high sodium intake in the development and maintenance of arterial hypertension. However, dietary sodium restriction reduces blood pressure in only a fraction of hypertensive patients. Studies in normotensive persons suggest that blacks and older persons excrete a sodium load less efficiently than persons of the same sex and race who are also matched for body weight and body surface area. Blacks show a greater natriuresis and decrease in blood pressure in response to volume contraction with furosemide administration than whites. These observations are consistent with an intrinsic renal abnormality in blacks and older persons, resulting in modest volume expansion. Such changes may contribute to sodium sensitivity and promote the development and maintenance of hypertension in persons with a high sodium intake.
影响因子：
158.5
作者：
BRENNER, BM;MEYER, TW;HOSTETTER, TH
通讯作者：
HOSTETTER, TH
血压正常的人的钠敏感性和抵抗力。
DOI：
10.1016/0002-9343(82)90537-x
发表时间：
1982
期刊：
The American journal of medicine
影响因子：
--
作者：
Luft,FC;Weinberger,MH;Grim,CE
通讯作者：
Grim,CE