The synapse assembly model

The synapse assembly model
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DOI:
10.1016/s1471-4906(02)02325-6
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发表时间:
2002-10-01
影响因子:
16.8
通讯作者:
Chakraborty, AK
Chakraborty, AK
中科院分区:
医学1区
文献类型:
--
作者:
Lee, SJE;Hori, Y;Chakraborty, AK

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最近开发了一个定量分析免疫突触组装机制的框架。这个模型使用偏微分方程来描述受体和配体之间的结合作用,约束条件是它们被嵌入到连接到细胞骨架复合体的相对可变形的膜中。
A framework for quantitative analysis of the mechanisms underlying immunological synapse assembly has been recently developed. This model uses partial differential equations to describe the binding interactions of receptors and ligands, with the constraint that they are embedded in apposed deformable membranes linked to a cytoskeletal complex.