Cushing's disease cycling over ten years.
Cushing's disease cycling over ten years.
复制标题
库欣病在十年内循环。
DOI：
10.1055/s-0029-1211003
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
M. Besser
中科院分区：
文献类型：
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作者：
V. Popović;D. Micić;M. Nes̆ovic;T. Howlett;I. Doniach;A. Kendereški;P. Djordjević;D. Manojlović;J. Micic;M. Besser
据报道，皮质醇分泌过多的周期被持续几天到几个月的缓解期所打断。在这项研究中，我们报告了一个10年随访的病人谁有四次发作的皮质醇增多症和库欣综合征与低钾血症和水肿和三个长期持续的自发缓解。这都是由促肾上腺皮质激素垂体腺瘤引起的。她表现出最长的缓解期，但记录在这种情况下，4.5年。周期性库欣综合征复发的诱发因素尚不明确，但我们的患者最后一次复发发生在分娩后两个月。我们已经讨论了标准动态试验在鉴别诊断库欣综合征中的持续不确定性。
Cycles of excessive cortisol secretion have been reported interposed with phases of remission lasting from few days to several months. In this study we report a ten year follow up on a patient who had four episodes of hypercortisolism and Cushing's syndrome associated with hypokalemia and edema and three long lasting spontaneous remissions. This was all caused by corticotroph pituitary adenoma. She demonstrated the longest phase of remission yet recorded in this condition, 4.5 years. The precipitating factors for the recurrence in cyclical Cushing's syndrome are not well defined, but the last recurrence in our patient appeared two months after delivery. We have discussed the continuing uncertainty of the standard dynamic tests in the differential diagnosis of Cushing's syndrome.