Chemokine (C-C motif) ligand 2 and chemokine (C-C motif) ligand 7 in angle-closure glaucoma
Chemokine (C-C motif) ligand 2 and chemokine (C-C motif) ligand 7 in angle-closure glaucoma
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DOI：
10.1111/aos.12696
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发表时间：
2016-05-01
影响因子：
3.4
通讯作者：
Jonas, Jost B.
中科院分区：
文献类型：
--
作者：
Gao, Xinbo;Huang, Wenbin;Jonas, Jost B.
目的比较急性闭角型青光眼(APAC)、原发性闭角型青光眼(PACG)和老年性白内障患者房水中趋化因子(C-C)配体2(CCL2)和趋化因子(C-C)配体7(CCL7)的浓度。青光眼发病至小梁切除术的时间间隔为19.49.8d。结果CCl2和CCl7的浓度分别为3037+/-501pg/ml和1127+/-141pg/ml，p=0.003；
PurposeTo compare the concentrations of chemokine (C-C motif) ligand 2 (CCL2) and chemokine (C-C motif) ligand 7 (CCL7) in aqueous humour of eyes with acute primary angle-closure (APAC), primary angle-closure glaucoma (PACG) or with age-related cataract.MethodsThe prospective investigation included a study group of 56 patients (24 patients with APAC; 32 patients with PACG) undergoing glaucoma surgery and a control group of 21 patients undergoing routine cataract surgery. The interval between glaucoma attack and trabeculectomy was 19.49.8days.ResultsThe concentrations of CCL2 (3037 +/- 501 versus 1127 +/- 141pg/ml; p=0.003) and CCL7 (10.5 +/- 2.4 versus 2.8 +/- 0.4pg/ml; p