The effect of hypocretin replacement therapy in a 3-year-old Weimaraner with narcolepsy.
The effect of hypocretin replacement therapy in a 3-year-old Weimaraner with narcolepsy.
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下丘脑分泌素替代疗法对患有发作性睡病的 3 岁威玛猎犬的效果。
DOI:
10.1111/j.1939-1676.2004.tb02590.x
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发表时间:
2004
影响因子:
2.6
通讯作者:
E. Mignot
中科院分区:
文献类型:
--
作者:
S. Schatzberg;K. Cutter;D. Nydam;J. Barrett;R. Penn;J. Flanders;A. Delahunta;Ling Lin;E. Mignot
Both the number ofattacks (NA) and elapsed time in collapse (ET) were mea-sured as an index of cataplexy severity. Further supportingthe diagnosis of narcolepsy and cataplexy, we measured adramatic response to IV yohimbine (Figs 1, 2; NA and ETwith no treatment: median, 6 collapses and 50.5 seconds,respectively; NA and ET with 0.048 mg/kg IV: median, 0.5collapses [P 5 .004] and 9.5 seconds [P 5 .005, Wilcoxonrank sum test], respectively).
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影响因子:
5.6
作者:
Nishino,S;Arrigoni,J;Shelton,J;Dement,WC;Mignot,E
通讯作者:
Mignot,E
影响因子:
--
作者:
Wagner,JL;Storb,R;Storer,B;Mignot,E
通讯作者:
Mignot,E
影响因子:
--
作者:
Mignot, E;Lammers, GJ;Nishino, S
通讯作者:
Nishino, S
影响因子:
7
作者:
Hungs, M;Fan, J;Mignot, E
通讯作者:
Mignot, E
DOI:
--
发表时间:
1990
期刊:
The Journal of pharmacology and experimental therapeutics
影响因子:
--
作者:
Nishino,S;Haak,L;Shepherd,H;Guilleminault,C;Sakai,T;Dement,WC;Mignot,E
通讯作者:
Mignot,E