A gas scintillator detector for 2D dose profile monitoring in pencil beam scanning and pulsed beam proton radiotherapy treatments.
A gas scintillator detector for 2D dose profile monitoring in pencil beam scanning and pulsed beam proton radiotherapy treatments.
复制标题
用于笔形束扫描和脉冲束质子放射治疗中二维剂量分布监测的气体闪烁体探测器。
DOI：
10.1088/1361-6560/aa6ce2
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发表时间：
2017
影响因子：
3.5
通讯作者：
Pankuch,M
中科院分区：
文献类型：
--
作者：
Vigdor,SE;Klyachko,AV;Solberg,KA;Pankuch,M
为了满足质子治疗过程中使用铅笔束扫描和/或脉冲束加速器的剂量测量需求，我们开发了一种氙气闪烁探测器（GSD），可以实时监测每脉冲的剂量和二维光束质心位置，具有高响应线性度和高瞬时剂量率。我们提出了GSD的设计考虑和在质子治疗诊所进行的光束测试的结果。除了在每个横向尺寸上σ为几百微米的空间分辨率和在大处理区域内相对剂量精度优于1%外，测试光束结果还揭示了GSD剂量归一化与剂量率、光束能量和气体杂质的依赖关系。结果表明，GSD技术有望为下一代离子束治疗提供剂量学方法的重要补充。
In order to address dosimetry demands during proton therapy treatments utilizing pencil beam scanning and/or pulsed beam accelerators, we have developed a xenon-filled gas scintillation detector (GSD) that can monitor delivered dose and 2D beam centroid position pulse-by-pulse in real time, with high response linearity up to high instantaneous dose rates. We present design considerations for the GSD and results of beam tests carried out at operating proton therapy clinics. In addition to demonstrating spatial resolution with σ of a few hundred microns in each transverse dimension and relative dose precision better than 1% over large treatment areas, the test beam results also reveal the dependence of the GSD dose normalization on dose rate, beam energy, and gas impurities. The results demonstrate the promise of the GSD technology to provide an important addition to dosimetry approaches for next-generation ion beam therapy.