Changing patterns of colorectal cancer in China over a period of 20 years
Changing patterns of colorectal cancer in China over a period of 20 years
复制标题
DOI：
10.3748/wjg.v11.i30.4685
复制
发表时间：
2005-08-14
影响因子：
4.3
通讯作者：
Gu, Jin
中科院分区：
文献类型：
--
作者：
Li, Ming;Gu, Jin
目的：方法：选取1980 ~ 1999年发表的21篇文献，按年龄、性别、肿瘤部位、分期、病理类型等因素分析我国结直肠癌发病的时间趋势。从20世纪80年代到90年代，结直肠癌患者的平均年龄有所增加。女性患者的比例上升。结直肠癌的分布以直肠癌为主。但近端结肠癌（包括横结肠和升结肠）的比例显著增加，同时直肠癌的比例下降。近20年来，远端结肠癌的百分比相似。在20世纪90年代，发现的B期患者在统计学上多于20世纪80年代。此外，数据库显示D期病例显著减少。腺癌的比例在20年中有所上升，而粘液腺癌的比例在20年中有所下降。结论：这些结果表明中国结直肠癌的模式正在发生变化。特别是在中国，由于升结肠和横结肠癌比例的增加，发生了近端转移。(C)2005年WJG出版社和Elsevier Inc. All rights reserved.
AIM: To determine whether any changes have occurred on the patterns of colorectal cancer in China.METHODS: Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology.RESULTS: From 1980s to 1990s, the mean age of the colorectal cancer patients has increased. The percentage of the female patients rose. The distribution of colorectal carcinoma shows a predominance of rectal cancer. However, the proportion of proximal colon cancer (including transverse and ascending colon) increased significantly accompanied by a decline in the percentage of rectal cancer. Similarity in the percentage of distal colon cancer between two decades was revealed. In the 1990s, statistically more Stage B patients were found than those in 1980s. In addition, databases show a significant decrease in the Stage D cases. The proportion of adenocarcinoma increased, but the mucinous adenocarcinoma decreased during two decades.CONCLUSION: These findings indicate that the pattern of colorectal cancer in China has been changing. Especially, a proximal shift due to the increasing proportion of ascending and transverse colon cancer has occurred in China. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.