MEDICATED EARLY WEANING TO OBTAIN PIGS FREE FROM PATHOGENS ENDEMIC IN THE HERD OF ORIGIN
MEDICATED EARLY WEANING TO OBTAIN PIGS FREE FROM PATHOGENS ENDEMIC IN THE HERD OF ORIGIN
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DOI：
10.1136/vr.106.6.114
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发表时间：
1980-01-01
影响因子：
2.2
通讯作者：
LYSONS, RJ
中科院分区：
文献类型：
--
作者：
ALEXANDER, TJL;THORNTON, K;LYSONS, RJ
进行了一项田间试验，以评估药物早期断奶对于使猪摆脱其起源群体中的一些地方性病原体的价值。试验包括来自封闭猪群的51头母猪，它们被分成7组在一个与世隔绝的分娩屋中分娩。各组母猪均在同一时间饲养，并于同日诱导产仔。他们最节俭的小猪在5天大时断奶，并被转移到一个孤立的早期断奶单元。在大约6周大的时候，他们被转移到3个孤立的成长单元中的一个，在那里他们被保持屠宰体重。其中5组母猪从进入产房到最大的仔猪断奶，一直服用高水平的硫蛋白和甲氧苄氨嘧磺胺制剂。他们的小猪从出生到10天大都服用了类似的药物。第1、7组母猪及其窝产的母猪不喂药。对5-11周龄的生猪、屠宰猪和不同日龄死亡或被宰杀的猪进行了猪肺炎支原体、败血波氏杆菌和结肠密螺旋体的检测，这些都是起源猪群中容易检测到的。没有发现支原体或波氏杆菌的证据。在屠宰时从一些猪身上发现了结肠密螺旋体，但从年轻猪身上没有发现。将来自药物组的37头公猪和母猪(37头)引入11个认为没有地方性肺炎的猪群，将13个引入到3个地方性肺炎的牛群。在10个没有地方性肺炎的牛群中，没有发现随后出现地方性肺炎的迹象。
A field trial was conducted to assess the value of medicated early weaning for obtaining pigs free from some of the pathogens endemic in their herd of origin. The trial comprised 51 sows from a closed herd, which were farrowed in an isolated farrowing house in 7 separate groups. The sows in each group were bred at the same time and induced to farrow on the same day. Their thriftiest piglets were weaned at 5 days of age and moved to an isolated early-weaning unit. At about 6 wk of age they were moved to 1 of 3 isolated grow-out units where they were held to slaughter weight. Sows in 5 of the groups were dosed with high levels of tiamulin and trimethoprim-sulfonamide preparations from their entry into the farrowing house until their biggest piglets were weaned. Their piglets were dosed with similar drugs from birth until 10 days of age. The 1st and 7th groups of sows and their litters were not medicated. Tests were carried out on pigs aged 5-11 wk, on slaughter pigs, and on pigs which died or were killed at different ages, for Mycoplasma hyopneumoniae, Bordetella bronchiseptica and colonic treponemes, which were readily detectable in the herd of origin. No evidence could be found of mycoplasma or bordetella. Colonic treponemes were recovered from some of the pigs at slaughter, but not from younger pigs. Boars and gilts (37) from the medicated groups were introduced into 11 herds thought to be free of enzootic pneumonia and 13 were introduced into 3 herds which had enzootic pneumonia. No subsequent signs of enzootic pneumonia were noted in 10 of the enzootic pneumonia-free herds.