Gastric adenocarcinoma presenting with gastric outlet obstruction in a child.
Gastric adenocarcinoma presenting with gastric outlet obstruction in a child.
复制标题
DOI：
10.1155/2014/527471
复制
发表时间：
2014
影响因子：
0.7
通讯作者：
Ourfali N
中科院分区：
文献类型：
--
作者：
Al-Hussaini A;Alghamdi S;Alsaaran R;Al-Kasim F;Habib Z;Ourfali N
儿童胃癌极为罕见，仅占所有胃肠道恶性肿瘤的 0.05%。在这里，我们报告第一例表现为胃出口梗阻的胃癌儿科病例。上消化道内镜检查显示胃窦粘膜明显增厚，闭塞幽门，胃小弯处有1.5cm×2cm的干净基底溃疡。狭窄的胃窦和幽门接受球囊扩张，胃窦活检显示幽门螺杆菌胃炎的证据。从胃溃疡边缘取出的活检显示印戒细胞型浸润，与胃腺癌一致。剖腹手术时，发现肝脏、胰头和肠系膜淋巴结转移。因此，胃癌被认为无法切除。该患者在开始化疗几个月后因晚期恶性肿瘤死亡。总之，本病例报告强调了儿童发生胃腺癌并出现胃出口梗阻的可能性。
Gastric carcinoma is extremely rare in children representing only 0.05% of all gastrointestinal malignancies. Here, we report the first pediatric case of gastric cancer presenting with gastric outlet obstruction. Upper endoscopy revealed a markedly thickened antral mucosa occluding the pylorus and a clean base ulcer 1.5 cm × 2 cm at the lesser curvature of the stomach. The narrowed antrum and pylorus underwent balloon dilation, and biopsy from the antrum showed evidence of Helicobacter pylori gastritis. The biopsy taken from the edge of the gastric ulcer demonstrated signet-ring-cell type infiltrate consistent with gastric adenocarcinoma. At laparotomy, there were metastases to the liver, head of pancreas, and mesenteric lymph nodes. Therefore, the gastric carcinoma was deemed unresectable. The patient died few months after initiation of chemotherapy due to advanced malignancy. In conclusion, this case report underscores the possibility of gastric adenocarcinoma occurring in children and presenting with gastric outlet obstruction.