The pyrimidinosome: Orchestrating pyrimidine biosynthesis and ferroptosis defense.
The pyrimidinosome: Orchestrating pyrimidine biosynthesis and ferroptosis defense.
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DOI:
10.1016/j.molcel.2023.07.013
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发表时间:
2023-08
期刊:
影响因子:
16
通讯作者:
Boyi Gan
中科院分区:
文献类型:
--
作者:
Boyi Gan
A recent study by Yang et al.1uncovers the pyrimidinosome, a multienzyme complex where enzymes from different subcellular compartments collaborate to enable efficient pyrimidine biosynthesis and ferroptosis defense, highlighting the remarkable adaptability of cellular metabolism and new therapeutic opportunities.