Digital hand atlas and web-based bone age assessment: system design and implementation
Digital hand atlas and web-based bone age assessment: system design and implementation
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DOI：
10.1016/s0895-6111(00)00026-4
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发表时间：
2000-09-01
影响因子：
5.7
通讯作者：
Gilsanz, V
中科院分区：
文献类型：
--
作者：
Cao, F;Huang, HK;Gilsanz, V
骨龄评估是一种经常在儿科患者中进行的程序，以评估他们的生长障碍。骨龄评估中常用的一种简单方法是通过对左手X线照片进行放射学检查，并与正常标准的Greulich-Pyle图谱模式的小参考集进行图谱匹配。然而，该方法可能会导致显着的偏差，在年龄评估，由于不同的观察员具有不同的培训水平。Greulich-Pyle图谱开发于20世纪50年代的中上层阶级的白色人口的基础上，也不完全适用于今天的儿童，特别是在其他种族groups.In本文中，我们提出了我们的系统设计和初步实施的数字手图谱和计算机辅助诊断（CAD）系统基于Web的骨龄评估。CAD系统是建立在现有的图像存档和通信系统（PACS），以及在互联网技术的最新进展。它包括一个手图集数据库，一个CAD模块和一个基于Java的Web用户界面。数字地图集是基于一个大的新的临床正常的手不同种族群体的图像集。一个关系型图像数据库系统被用来组织手部图像，其提取的定量特征和患者数据。数字图谱消除了目前过时的Greulich-Pyle图谱的缺点，并允许骨龄评估计算机化。基于Java的Web用户界面允许用户从浏览器与手部图像数据库进行交互。用户可以使用Web浏览器将临床手部图像推送到CAD服务器进行骨龄评估。然后提取反映骨骼成熟度的检查图像上的定量特征，并与图谱数据库中的模式进行比较，以评估骨龄。基于开放式系统互联网技术的数字图谱法为定量、准确、经济地评估骨龄提供了一种补充或替代传统骨龄的方法。(C)2000年由爱思唯尔科学有限公司出版。
Bone age assessment is a procedure frequently performed in pediatric patients to evaluate their growth disorder. A simple method commonly used in bone age assessment is atlas matching by a radiological examination of a left-hand radiograph against a small reference set of Greulich-Pyle atlas patterns of normal standards. The method however can lead to significant deviation in age assessment, due to a variety of observers with different levels of training. The Greulich-Pyle atlas developed in the 1950s based on middle upper class white populations, is also not fully applicable for children of today, especially regarding the standard development in other racial groups.In this paper, we present our system design and initial implementation of a digital hand atlas and computer-aided diagnostic (CAD) system for Web-based bone age assessment. The CAD system is built on top of existing picture archiving and communication system (PACS), as well as recent advances in Internet technology. It consists of a hand atlas database, a CAD module and a Java-based Web user interface. The digital atlas is based on a large new set of clinically normal hand images of diverse ethnic groups. A relational image database system is used to organize hand images, their extracted quantitative features and patient data. The digital atlas removes the disadvantages of the currently out-of-date Greulich-Pyle atlas and allows the bone age assessment to be computerized. The Java-based Web user interface allows users to interact with the hand image database from browsers. Users can use a Web browser to push a clinical hand image to the CAD server for a bone age assessment. Quantitative features on the examined image, which reflect the skeletal maturity, are then extracted and compared with patterns from the atlas database to assess the bone age. The digital atlas method based on open system Internet technology provides an alternative to supplement or replace the traditional one for a quantitative, accurate and cost-effective assessment of bone age. (C) 2000 published by Elsevier Science Ltd.