Tendon structure changes after maximal exercise in the Thoroughbred horse: Use of ultrasound tissue characterisation to detect in vivo tendon response
Tendon structure changes after maximal exercise in the Thoroughbred horse: Use of ultrasound tissue characterisation to detect in vivo tendon response
复制标题
DOI：
10.1016/j.tvjl.2012.04.024
复制
发表时间：
2012-12-01
影响因子：
2.2
通讯作者：
Cook, J. L.
中科院分区：
文献类型：
--
作者：
Docking, S. I.;Daffy, J.;Cook, J. L.
纯种马指浅屈肌腱(SDFT)对机械刺激的反应仅限于体外细胞培养研究，主要集中在关键基质蛋白的基因表达。目前还不确定在运动过程中，体外结果在马的肌腱上的转化情况如何。目前的研究使用超声组织特征(UTC)扫描赛前和赛后的SDFT来检测肌腱结构在最大运动量时的变化。UTC使用连续的横向超声图像来评估肌腱的动力学，这与肌腱的三维超结构的变化密切相关。使用UTC，可以检测到肌腱动力学的细微变化，与比赛前相比，比赛后1天和2天代表排列整齐的胶原肌腱束的像素减少(P<；0.05)。这些肌腱的环境模式在第3天恢复到基线水平。这种环境模式的变化在对照马中未见。结论：利用UTC可以检测到极量运动后SOFT的短期变化。(C)2012爱思唯尔有限公司。保留所有权利。
Investigations into the response of the superficial digital flexor tendon (SDFT) of the Thoroughbred horse to mechanical stimuli have been limited to in vitro cell culture studies focused primarily on gene expression of critical matrix proteins. It is uncertain how well in vitro outcomes translate to the tendon of the horse during exercise. The current study examined changes in tendon structure in response to maximal exercise using ultrasound tissue characterisation (UTC) to scan the SDFT prior to and after competitive racing. UTC uses contiguous transverse ultrasound images to assess the dynamics of the echopattern, which has a close relationship with changes in the 3-D ultra-structure of the tendon.Using UTC, it was possible to detect subtle changes in the dynamics of the echopattern, with a reduction in pixels that represent aligned and integer collagen tendon bundles on days 1 and 2 post-race when compared to pre-race (P < 0.05). The echopattern of these tendons returned to baseline on day 3. This change in echopattern was not seen in control horses. It was concluded that short-term changes in the SOFT following maximal exercise could be detected using UTC. (C) 2012 Elsevier Ltd. All rights reserved.