Limitations of venous thromboembolism risk assessment models in medical patients: Response to "Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation".
Limitations of venous thromboembolism risk assessment models in medical patients: Response to "Unmet definitions in thromboprophylaxis for hospitalized medical patients: An appraisal for the need of recommendation".
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DOI：
10.1016/j.rpth.2022.100027
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发表时间：
2023-01
影响因子：
4.6
通讯作者：
Cohen, Alexander T.
中科院分区：
文献类型：
--
作者：
Er, Chaozer;Cohen, Alexander T.
尊敬的编辑，我们饶有兴趣地阅读了 Ferreira 及其同事最近发表的一篇评论，描述了住院患者血栓预防方面不精确且不明确的领域 [1]。然而，我们认为该领域还存在其他重要的不确定性，特别是与可用风险评估模型（RAM）的局限性有关。理想的 RAM 是在合适的人群中正确得出的，并经过外部验证，以在考虑静脉血栓栓塞 (VTE) 和出血的风险后准确识别开始血栓预防的风险益处 [2, 3]。它的使用应该会提高血栓预防率并减少入院相关的 VTE [3]。它应该具有成本效益且易于使用[3]。当前的 RAM 具有以下限制：
Dear Editor, We read with interest the recent review of Ferreira and colleagues describing imprecise and unclear areas in thromboprophylaxis for hospitalized medical patients [1]. However, we consider that there are other important uncertainties in this field, particularly in relation to limitations of available risk assessment models (RAMs). An ideal RAM is properly derived in a suitable population and externally validated to accurately identify the risk benefit of initiating thromboprophylaxis after factoring in both the risks of venous thromboembolism (VTE) and bleeding [2, 3]. Its use should lead to improvements in thromboprophylaxis rates and reduced hospital admission–related VTE [3]. It should be cost effective and simple to use [3]. Current RAMs have the following limitations:
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