Rickettsia felis, an Emerging Flea-Borne Rickettsiosis.
Rickettsia felis, an Emerging Flea-Borne Rickettsiosis.
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DOI：
10.1007/s40475-016-0070-6
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发表时间：
2016
影响因子：
5.4
通讯作者：
Macaluso KR
中科院分区：
文献类型：
--
作者：
Brown LD;Macaluso KR
猫立克次体是一种新发现的虫媒立克次体病原体，也是蚤媒斑点热的病原体。1991年，美国首次将其描述为一种人类病原体。猫现已在世界各地被发现，并被认为是非洲发烧的常见原因。这种病原体的世界性分布归功于猫蚤（Ctenocephalides felis）的同样广泛的发生，猫蚤是R.猫尽管R.猫立克次体是致病性立克次体中较新的成员，对立克次体的基本知识有限。猫的生物学继续阻碍这种独特细菌的研究进展。这是一个全面的审查检查什么是已知的和未知的相对于R。猫的传播生物学，疾病的流行病学和遗传学，并深入了解需要调查的领域。
Rickettsia felis is an emerging insect-borne rickettsial pathogen and the causative agent of flea-borne spotted fever. First described as a human pathogen from the USA in 1991, R. felis is now identified throughout the world and considered a common cause of fever in Africa. The cosmopolitan distribution of this pathogen is credited to the equally widespread occurrence of cat fleas (Ctenocephalides felis), the primary vector and reservoir of R. felis. Although R. felis is a relatively new member of the pathogenic Rickettsia, limited knowledge of basic R. felis biology continues to hinder research progression of this unique bacterium. This is a comprehensive review examining what is known and unknown relative to R. felis transmission biology, epidemiology of the disease, and genetics, with an insight into areas of needed investigation.