Effect of bone chip orientation on quantitative estimates of changes in bone mass using digital subtraction radiography.
Effect of bone chip orientation on quantitative estimates of changes in bone mass using digital subtraction radiography.
复制标题
骨芯片方向对使用数字减影射线照相术定量估计骨量变化的影响。
DOI：
10.1034/j.1600-0765.2003.00015.x
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发表时间：
2003
影响因子：
3.5
通讯作者：
Dunn,StanleyM
中科院分区：
文献类型：
--
作者：
Mol,André;Dunn,StanleyM
目的：评估任意形状骨片的方向对使用数字减影x线摄影评估骨丢失和真实矿物质损失之间的相关性的影响。方法：将20个任意形状的骨片（干重1-10 mg）分别放置在干齿状半下颌骨的牙间牙槽骨的上舌面。在获得第一张基线图像后，将每个芯片旋转90度，并捕获第二张x光片。在没有骨芯片的情况下，将下颌骨绕垂直轴旋转0度、1度、2度、4度和6度后，创建后续图像。采用铝阶梯片强度对每对图像进行图像强度归一化。对随访图像进行配准，并使用投影标准化进行几何标准化。骨片干燥干燥，用原子吸收法分析钙含量。结果：不同骨片取向对骨丢失的x线估测无显著差异（Wilcoxon:P < 0.05）。所有旋转的两组估计值之间的相关性为0.93 （Spearman:P< 0.05）。线性回归分析表明，两者的相关性没有明显差异（和）。结论：在数字减影摄影中，任意形状骨片的空间方向对骨量变化的定量估计没有显著影响。这些结果是在存在高达6度的不可逆投影误差的情况下获得的，并且在图像重建和图像配准中应用了投影标准化。
Objectives:To assess the effect of the orientation of arbitrarily shaped bone chips on the correlation between radiographic estimates of bone loss and true mineral loss using digital subtraction radiography.Methods:Twenty arbitrarily shaped bone chips (dry weight 1–10 mg) were placed individually on the superior lingual aspect of the interdental alveolar bone of a dry dentate hemi‐mandible. After acquiring the first baseline image, each chip was rotated 90 degrees and a second radiograph was captured. Follow‐up images were createdwithoutthe bone chips and after rotating the mandible 0, 1, 2, 4, and 6 degrees around a vertical axis. Aluminum step tablet intensities were used to normalize image intensities for each image pair. Follow‐up images were registered and geometrically standardized using projective standardization. Bone chips were dry ashed and analyzed for calcium content using atomic absorption.Results:No significant difference was found between the radiographic estimates of bone loss from the different bone chip orientations (Wilcoxon:P> 0.05). The correlation between the two series of estimates for all rotations was 0.93 (Spearman:P< 0.05). Linear regression analysis indicated that both correlates did not differ appreciably ( and ).Conclusion:It is concluded that the spatial orientation of arbitrarily shaped bone chips does not have a significant impact on quantitative estimates of changes in bone mass in digital subtraction radiography. These results were obtained in the presence of irreversible projection errors of up to six degrees and after application of projective standardization for image reconstruction and image registration.