New lyssavirus genotype from the Lesser Mouse-eared bat (Myotis blythi), Kyrghyzstan
New lyssavirus genotype from the Lesser Mouse-eared bat (Myotis blythi), Kyrghyzstan
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DOI：
10.3201/eid0903.020252
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发表时间：
2003-03-01
影响因子：
11.8
通讯作者：
Botvinkin, AD
中科院分区：
文献类型：
--
作者：
Arai, YT;Kuzmin, IV;Botvinkin, AD
The Aravan virus was isolated from a Lesser Mouse-eared Bat (Myotis blythi) in the Osh region of Kyrghyzstan, central Asia, in 1991. We determined the complete sequence of the nucleoprotein (N) gene and compared it with those of 26 representative lyssaviruses obtained from databases. The Aravan virus was distinguished from seven distinct genotypes on the basis of nucleotide and amino acid identity. Phylogenetic analysis based on both nucleotide and amino acid sequence showed that the Aravan virus was more closely related to genotypes 4, 5, and-to a lesser extent-6, which circulates among insectivorus bats in Europe and Africa. The Aravan virus does not belong to any of the seven known genotypes of lyssaviruses, namely, rabies, Lagos bat, Mokola, and Duvenhage viruses and European bat lyssavirus 1, European bat lyssavirus 2, and Australian bat lyssavirus. Based on these data, we propose a new genotype or the Lyssavirus genus.
