WOMBAT - A tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML)

WOMBAT - A tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML)
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DOI:
10.1631/jzus.2007.b0815
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发表时间:
2007-10-01
影响因子:
5.1
通讯作者:
Karin, Meyer
Karin, Meyer
中科院分区:
生物学2区
文献类型:
--
作者:
Karin, Meyer

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袋熊是一个对连续性状进行定量遗传分析的软件包,符合线性混合模型;协方差分量的估计和由此产生的遗传参数是通过限制最大似然法获得的。模型的范围很广,包括许多性状、多个固定和随机效应、选定的遗传协方差结构、随机回归模型和降阶估计。袋熊使用最新的数值和计算方法。再加上高效编译器的使用,这将生成适合大规模分析的快速可执行程序。对袋熊的使用进行了双变量分析。该包由可执行程序、手册和一组工作示例组成,可在linux和windows环境下使用,可从http://agbu.une.edu.au/:_kmeyer/wombat.html免费下载
WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable program, available for LINUX and WINDOWS environments, manual and a set of worked example, and can be downloaded free of charge from http://agbu.une.edu.au/:_kmeyer/wombat.html