The impact of type 1 diabetes on young adults' health-related quality of life
The impact of type 1 diabetes on young adults' health-related quality of life
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DOI：
10.1186/s12955-020-01370-8
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发表时间：
2020-05-12
影响因子：
3.6
通讯作者：
van Staa, AnneLoes
中科院分区：
文献类型：
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作者：
Bronner, Madelon B.;Peeters, Marielle A. C.;van Staa, AnneLoes
研究背景对于1型糖尿病（T1 DM）患者来说，青年期是一个具有挑战性的时期，因为他们在管理一种要求苛刻的疾病的同时面临着多种生活转变。这会导致健康相关生活质量（HRQOL）受损。我们评估HRQOL在荷兰的一个队列中的年轻人与T1 DM，并与荷兰正常组的健康的年轻人和年轻人与慢性病。MethodsWe的结果进行了比较，在一个更大的评估研究中收集的数据在荷兰全国范围内的样本，包括12家参与医院的过渡期护理与T1 DM的年轻人。这些数据来自年轻T1 DM患者转入成人护理后完成的在线问卷调查。HRQOL是自我报告的儿童生活质量量表的年轻人（PedsQL-YA）。Results 165与T1 DM的年轻人参加（44.2%的反应），他们得分显着不如健康的同龄人在所有领域的HRQOL，除了社会功能。特别是，在学校或工作中的表现比正常组差。研究组的HRQOL评分与患有慢性疾病的年轻人的正常评分相当，尽管患有T1 DM的年轻人的身体和社会功能更好。四分之一（26.1%）的所有年轻人与T1 DM报告fatigue.ConclusionsDuring过渡到成年，年轻人与T1 DM的斗争，以保持管理疾病的需求和他们的生活之间的平衡。他们中的许多人在工作或学校遇到问题，并遭受疲劳。这些研究结果强调需要定期评估HRQOL，并讨论在临床实践中的工作和教育相关的问题。
BackgroundYoung adulthood is a challenging period for people with diabetes mellitus type 1 (T1DM) as they are facing multiple life transitions while managing a demanding disease. This poses a risk for impaired health-related quality of life (HRQOL). We assessed HRQOL in a cohort of young adults with T1DM in the Netherlands, and compared outcomes with those of Dutch norm groups of healthy young adults and young adults with a chronic disease.MethodsWe analyzed data collected in a larger evaluation study on transitional care for young adults with T1DM in a nationwide sample in the Netherlands, including twelve participating hospitals. These data had been obtained from online questionnaires completed by young adults with T1DM after they had transferred to adult care. HRQOL was self-reported with the Pediatric Quality of Life Inventory for young adults (PedsQL-YA).ResultsOne hundred and sixty-five young adults with T1DM participated (44.2% response); and they scored significantly worse than did healthy peers on all domains of HRQOL, except social functioning. Particularly, functioning at school or work was worse than that of the norm group. The study group's HRQOL-scores were comparable to norm scores of young adults with chronic diseases, although the physical and social functioning of young people with T1DM was better. One quarter (26.1%) of all young adults with T1DM reported fatigue.ConclusionsDuring transition to adulthood, young adults with T1DM struggle to maintain a balance between the demands of managing a disease and their life. Many of them encounter problems at work or school, and suffer from fatigue. These findings underscore the need to regularly assess HRQOL, and to discuss work- and education-related issues in clinical practice.