Hidden epidemic of macrolide-resistant pneumococci.
Hidden epidemic of macrolide-resistant pneumococci.
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DOI:
10.3201/eid1106.050147
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发表时间:
2005-06
影响因子:
11.8
通讯作者:
Lonks JR
中科院分区:
文献类型:
--
作者:
Klugman KP;Lonks JR
Community-acquired respiratory tract infections (RTIs) account for a substantial proportion of outpatient antimicrobial drug prescriptions worldwide. Concern over the emergence of multidrug resistance in pneumococci has largely been focused on penicillin-resistant Streptococcus pneumoniae. Macrolide antimicrobial drugs have been widely used to empirically treat community-acquired RTIs because of their efficacy in treating both common and atypical respiratory pathogens, including S. pneumoniae. However, increased macrolide use has been associated with a global increase in pneumococcal resistance, which is leading to concern over the continued clinical efficacy of the macrolides to treat community-acquired RTIs. We provide an overview of macrolide-resistant S. pneumoniae and assess the impact of this resistance on the empiric treatment of community-acquired RTIs.
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影响因子:
4.9
作者:
Dagan, R;Leibovitz, E;Yagupsky, P
通讯作者:
Yagupsky, P
DOI:
10.1164/ajrccm.159.6.9808049
发表时间:
1999-06-01
影响因子:
24.7
作者:
Ewig, S;Ruiz, M;Mensa, J
通讯作者:
Mensa, J
影响因子:
11.8
作者:
Farrell DJ;Jenkins SG;Brown SD;Patel M;Lavin BS;Klugman KP
通讯作者:
Klugman KP
影响因子:
--
作者:
Heffelfinger, JD;Dowell, SF;Whitney, CG
通讯作者:
Whitney, CG
影响因子:
5.2
作者:
Jacobs, MR;Felmingham, D;Grüneberg, RN
通讯作者:
Grüneberg, RN