Influence of dietary behavior on the circadian rhythm of the autonomic nervous system as assessed by heart rate variability
Influence of dietary behavior on the circadian rhythm of the autonomic nervous system as assessed by heart rate variability
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通过心率变异性评估饮食行为对自主神经系统昼夜节律的影响
DOI：
10.1016/j.physbeh.2013.05.010
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发表时间：
2013
期刊：
影响因子：
2.9
通讯作者：
(他6名)
中科院分区：
文献类型：
--
作者：
Yoshizaki;T;(他6名)
研究背景昼夜节律失调对人体健康有害。然而，只有少数研究研究了晚餐对人类昼夜节律系统的影响。本研究的目的是探讨延迟进餐是否影响昼夜节律的评估心率变异性（HRV）。方法7名健康男性（年龄22.4 ± 0.4岁）参加了这项研究，其中包括延迟进餐时间5小时，两周。在本研究之前，参与者的常规用餐时间为08：00、13：00和18：00（基线）。在干预期间，每餐均在13：00、18：00和23：00（晚餐时间）提供。根据24小时心电图记录中QRS波群中每个尖峰上升相的脉冲计算R-R间期，通过HRV评估昼夜节律变化。使用频谱分析计算低频（LF）与高频（HF）功率的比值（LF/HF）和HF功率与总功率的比值（%HF）。HRV变量的相位和振幅在24小时内的数学获得与双余弦analysis.ResultsThe LF功率，HF功率和%HF在24小时内的acrophase和振幅基线和晚餐时间之间没有显着差异。另一方面，基线和晚餐时间之间的心率（95%CI，1.1-3.8小时），标准差的R-R间期（95%CI，2.5-4.4小时）和LF/HF（95%CI，1.1-2.3小时）acrophase显着不同conclusionsOur研究结果表明，延迟进餐时间移动的自主神经系统的昼夜节律的相位。
BackgroundMisalignment of circadian systems is detrimental to human health. However, only a few studies have examined the influence of late meals on the human circadian system. The purpose of this study was to investigate whether delayed meals affect circadian rhythm as assessed by heart rate variability (HRV).MethodsSeven healthy men (aged 22.4 ± 0.4 years) participated in this study, which involved delaying mealtimes by 5 h for two weeks. Prior to this study, the regular mealtimes of participants were at 08:00, 13:00, and 18:00 (Baseline). During the intervention, each meal was provided at 13:00, 18:00 and 23:00 (Late mealtimes). Circadian variation was assessed by HRV based on R–R intervals calculated from a pulse at the rising phase of each spike in the QRS complex in a 24-h electrocardiograph record. The ratio of low frequency (LF) to high frequency (HF) power (LF/HF) and the ratio of HF power to total power (%HF) were calculated using spectral analysis. The phase and amplitude of HRV variables in a 24-h period were mathematically obtained with double cosinor analysis.ResultsThe acrophase and amplitude for LF power, HF power and %HF in a 24-h period were not significantly different between Baseline and Late mealtimes. On the other hand, the acrophase significantly differed between Baseline and Late mealtimes for heart rate (95%CI, 1.1–3.8 h), standard deviation of R–R intervals (95%CI, 2.5–4.4 h) and LF/HF (95%CI, 1.1–2.3 h).ConclusionsOur findings suggest that delayed mealtimes shift the phase of circadian rhythm of the autonomic nervous system.