Input–output relationships of the dorsal nucleus of the lateral lemniscus: Possible substrate for the processing of dynamic spatial cues
Input–output relationships of the dorsal nucleus of the lateral lemniscus: Possible substrate for the processing of dynamic spatial cues
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外侧丘系背核的输入-输出关系：处理动态空间线索的可能基础
DOI：
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
R. L. Marie
中科院分区：
文献类型：
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作者：
A. Shneiderman;A. Shneiderman;D. Stanforth;C. Henkel;R. L. Marie;R. L. Marie
听觉系统的一个组织原则是最佳调谐频率的渐进表示。叠加在这个tonotopy是核位置组织，其中一些是与不同的空间线索的处理。在本研究中，我们相关的不对称输出的外侧丘系（DNLL）的两个下丘（IC），与不对称的输入DNLL从两个外侧上级橄榄（LSO）。在IC单侧注射逆行示踪剂的情况下，绘制了具有交叉和非交叉投射的DNLL神经元的位置。我们发现了一个有序的背腹向输出的进展，概括了DNLL的音调。此外，我们在DNLL的腹侧（高频）部分发现了核定位组织。在DNLL中，投射到对侧IC腹内侧（高频）部分的神经元优先位于腹外侧;在DNLL中，投射到同侧IC腹内侧部分的神经元优先位于腹内侧。这种输出的部分隔离对应于两个LSO的输入的部分隔离，在LSO中接收到紧密匹配的顺行示踪剂的双边注射的情况下。DNLL的腹侧部接受来自对侧LSO的内侧重投射和来自同侧LSO的外侧重投射。研究结果表明，在腹侧部分的DNLL之间的输入从两个LSO和输出到两个IC的直接关系。这种隔离的途径在DNLL中的可能作用进行了讨论，静态和动态的空间线索的处理。J. Comp.神经元410：265-276，1999.© 1999 Wiley利斯公司
One organizing principle of the auditory system is the progressive representation of best tuning frequency. Superimposed on this tonotopy are nucleotopic organizations, some of which are related to the processing of different spatial cues. In the present study, we correlated asymmetries in the outputs of the dorsal nucleus of the lateral lemniscus (DNLL) to the two inferior colliculi (ICs), with asymmetries in the inputs to DNLL from the two lateral superior olives (LSOs). The positions of DNLL neurons with crossed and uncrossed projections were plotted from cases with unilateral injections of retrograde tracers in the IC. We found an orderly dorsal‐to‐ventral progression to the output that recapitulated the tonotopy of DNLL. In addition, we found a nucleotopic organization in the ventral (high‐frequency) part of DNLL. Neurons with projections to the ventromedial (high‐frequency) part of the contralateral IC were preferentially located ventrolaterally in DNLL; those with projections to the ventromedial part of the ipsilateral IC were preferentially located ventromedially in DNLL. This partial segregation of outputs corresponded with a partial segregation of inputs from the two LSOs in cases which received closely matched bilateral injections of anterograde tracers in LSO. The ventral part of DNLL received a heavy projection medially from the opposite LSO and a heavy projection laterally from the ipsilateral LSO. The findings suggest a direct relationship in the ventral part of the DNLL between inputs from the two LSOs and outputs to the two ICs. Possible roles for this segregation of pathways in DNLL are discussed in relation to the processing of static and dynamic spatial cues. J. Comp. Neurol. 410:265–276, 1999. © 1999 Wiley‐Liss, Inc.
影响因子：
2.5
作者：
COVEY, E
通讯作者：
COVEY, E
听觉运动引起下丘神经元的方向依赖性感受野变化。
DOI：
10.1152/jn.1998.79.4.2040
发表时间：
1998
期刊：
Journal of neurophysiology.
影响因子：
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作者：
Wilson,WW;O'Neill,WE
通讯作者：
O'Neill,WE