Subarachnoid and intracerebral hemorrhage in patients with churg-strauss syndrome: two case reports.

Subarachnoid and intracerebral hemorrhage in patients with churg-strauss syndrome: two case reports.
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DOI:
10.7461/jcen.2012.14.3.255
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发表时间:
2012-09
期刊:
Journal of cerebrovascular and endovascular neurosurgery
影响因子:
--
通讯作者:
Lim YC
Lim YC
中科院分区:
其他
文献类型:
--
作者:
Go MH;Park JU;Kang JG;Lim YC

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Churg-Strauss综合征(CSS)是一种中小血管的系统性坏死性血管炎,与血管外嗜酸性肉芽肿、外周嗜酸性粒细胞增多和哮喘有关。CSS的确切病因尚不清楚。这种综合征通常影响肺、周围神经、皮肤、心脏和胃肠道,但很少影响中枢神经系统。CSS患者的蛛网膜下腔和脑内出血极为罕见;然而,临床医生应考虑CSS可能是颅内出血及其高死亡率和发病率的原因。作者报告了两例蛛网膜下腔出血和脑内出血的CSS,并讨论了CSS的简要回顾。
Churg-Strauss syndrome (CSS) is a systemic necrotizing vasculitis of the small and medium vessels, associated with extravascular eosinophilic granulomas, peripheral eosinophilia, and asthma. The exact etiology of CSS is unknown. This syndrome commonly affects the lungs, peripheral nerves, skin, heart, and gastrointestinal tract, but rarely the central nervous system. Subarachnoid and intracerebral hemorrhage in CSS patients is extremely rare; however, clinicians should consider that CSS may be a cause of intracranial hemorrhage and its high rate of mortality and morbidity. The authors report on two cases of subarachnoid and intracerebral hemorrhage with CSS and discuss a brief review of CSS.