Epidemiological link between wastewater and human vancomycin-resistant Enterococcus faecium isolates
Epidemiological link between wastewater and human vancomycin-resistant Enterococcus faecium isolates
复制标题
DOI：
10.1007/s00284-008-9113-0
复制
发表时间：
2008-05-01
影响因子：
2.6
通讯作者：
Pourshafie, Mohammad R.
中科院分区：
文献类型：
--
作者：
Talebi, Malihe;Rahimi, Fateh;Pourshafie, Mohammad R.
我们调查了从废水 (n = 593) 和临床 (n = 450) 样本中分离出的耐万古霉素肠球菌 (VRE) 的流行情况，并比较了分离株之间的遗传关联。在全部样本中，来自污水 (n = 19) 和临床 (n = 19) 分离株的 38 株屎肠球菌 (3.6%) 被发现对万古霉素高度耐药。这两个来源的大多数 VRE 分离株表现出不同的表型和基因分型模式。与此同时，在从废水和人类临床分离株中获得的 VRE 中发现了一种常见的脉冲场凝胶电泳模式，表明存在流行病学联系。
We investigated the prevalence of vancomycin-resistant enterococci (VRE) isolated from wastewater (n = 593) and clinical (n = 450) samples, and the genetic linkage between the isolates was compared. Out of the total samples, 38 Enterococcus faecium (3.6%) from sewage (n = 19) and clinical (n = 19) isolates were found to be highly resistant to vancomycin. The majority of the VRE isolates from the two sources showed distinct phenotyping and genotyping patterns. At the same time, one common pulsed-field gel electrophoresis pattern was found among the VRE obtained from wastewater and human clinical isolates, suggestive of an epidemiological link.