EPIDEMIOLOGY OF PROSTATIC-CANCER - A CASE-CONTROL STUDY
EPIDEMIOLOGY OF PROSTATIC-CANCER - A CASE-CONTROL STUDY
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DOI：
10.1002/pros.2990170303
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发表时间：
1990-01-01
期刊：
影响因子：
2.8
通讯作者：
WIJAYASINGHE, C
中科院分区：
文献类型：
--
作者：
FINCHAM, SM;HILL, GB;WIJAYASINGHE, C
在阿尔伯塔进行了一项以人群为基础的前列腺癌病例对照研究，以确定与该疾病相关的危险因素。病例为382例新诊断的前列腺癌患者和625例对照组，与病例的预期年龄分布相匹配，从健康保险名册中随机选择。受试者在他们的家中进行了采访，使用预先测试的问卷，包括有关种族，教育，青春期，婚姻史，家族史，居住地，供水，吸烟和饮食的问题。与患前列腺癌风险显著相关的因素包括种族（英国高，乌克兰低），教育（小学高，大学低），初婚年龄（早期高，晚期低），家族史（前列腺癌亲属的高风险），以及病例儿童中男性气质的增加。吸烟、职业、病史、出生地、居住地、供水和饮食方面的结果普遍为阴性。
A population-based case-control study of prostatic cancer in Alberta was undertaken to determine the risk factors associated with the disease. Cases were 382 newly diagnosed prostatic cancer patients and 625 controls, group-matched to the anticipated age distribution of the cases, chosen at random from the health insurance roster. Subjects were interviewed in their homes by using a pre-tested questionnaire including questions related to ethnic group, education, puberty, marital history, family history, residence, water supply, smoking, and diet. Factors significantly related to the risk of developing prostatic cancer included ethnic group (British high, Ukrainian low), education (elementary high, university low), age at first marriage (early high, late low), family history (high risk for those with relatives with prostatic cancer), and increased masculinity among the children of cases. The results with respect to smoking, occupation, medical history, birthplace, residence, water supply, and diet were generally negative.