High-speed chemical imaging inside a microfluidic channel
High-speed chemical imaging inside a microfluidic channel
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DOI：
10.1016/j.snb.2013.12.090
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发表时间：
2014-04-01
影响因子：
8.4
通讯作者：
Yoshinobu, Tatsuo
中科院分区：
文献类型：
--
作者：
Miyamoto, Ko-ichiro;Itabashi, Akinori;Yoshinobu, Tatsuo
在这项研究中，开发了一种高速化学成像系统，用于微流体通道内部的可视化。在光寻址电位传感器（LAPS）的传感器表面上构建了一个微流控通道，在该通道上，可以在光纤照明的多达64个点处并行测量离子浓度。以每秒100帧（fps）的最大速率记录微流体通道内pH分布的时间变化。即使在111 mm/s的流速下，高帧速率也允许通道中的移动界面和塞子的可视化，这表明基于塞子的微流体装置用于流动注射分析（FIA）的可行性。(C)2014爱思唯尔有限公司版权所有。
In this study, a high-speed chemical imaging system was developed for visualization of the interior of a microfluidic channel. A microfluidic channel was constructed on the sensor surface of the light-addressable potentiometric sensor (LAPS), on which the ion concentrations could be measured in parallel at up to 64 points illuminated by optical fibers. The temporal change of pH distribution inside the microfluidic channel was recorded at a maximum rate of 100 frames per second (fps). The high frame rate allowed visualization of moving interfaces and plugs in the channel even at a flow velocity of 111 mm/s, which suggests the feasibility of plug-based microfluidic devices for flow-injection analysis (FIA). (C) 2014 Elsevier B.V. All rights reserved.