PREVALENCE OF YERSINIA AMONG WILD SIKA DEER (CERVUS NIPPON) AND BOARS (SUS SCROFA) IN JAPAN
PREVALENCE OF YERSINIA AMONG WILD SIKA DEER (CERVUS NIPPON) AND BOARS (SUS SCROFA) IN JAPAN
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DOI：
10.7589/2019-04-094
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发表时间：
2019-12
期刊：
影响因子：
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通讯作者：
Tatsuki Takahashi;H. Kabeya;Shingo Sato;A. Yamazaki;Y. Kamata;K. Taira;H. Asakura;H. Sugiyama;S. Takai;S. Maruyama
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文献类型：
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作者：
Tatsuki Takahashi;H. Kabeya;Shingo Sato;A. Yamazaki;Y. Kamata;K. Taira;H. Asakura;H. Sugiyama;S. Takai;S. Maruyama
摘要：调查了日本野生梅花鹿(Cervus Nippon)和野猪(Sus Scrofa)中耶尔森氏菌的流行情况，包括耶尔森氏菌、小肠结肠炎耶尔森氏菌和假结核耶尔森氏菌。野鹿耶尔森氏菌感染率为75%(207/277)，公猪耶尔森氏菌感染率为74%(40/54)。共分离到9种耶尔森氏菌417株，其中以1A型耶尔森菌的分离率最高(48%，200/417)。从2头鹿分离到致病性小肠结肠炎耶尔森氏菌1B/O：8，从2头公猪和1头鹿分离出假结核耶尔森氏菌群3和群4。致病性小肠结肠炎耶尔森菌1B/O：8株携带4个毒力基因(ail、ystA、yada和virF)，假结核杆菌血清群3和4株携带3个毒力基因(inv、yada和lcrF)。虽然小肠结肠炎耶尔森菌1B/O：8和假结核耶尔森菌对几乎所有测试的抗菌药都敏感，但这两株小肠结肠炎耶尔森菌1B/O：8对阿奇霉素和氨苄西林耐药，而3株假结核耶尔森菌只对阿奇霉素耐药。这些发现表明，野鹿和野猪可能是引起人类耶尔森氏病的病原体的重要宿主。
Abstract: We examined the prevalence of Yersinia, including pathogenic species such as Yersinia enterocolitica and Yersinia pseudotuberculosis, among wild sika deer (Cervus nippon) and boars (Sus scrofa) captured in Japan. The prevalence of Yersinia in the wild deer was 75% (207/277) and in the boars was 74% (40/54). A total of 417 isolates of nine Yersinia species were isolated from the animals examined: the largest number of isolates (48%, 200/417) were Y. enterocolitica biotype 1A. Pathogenic Y. enterocolitica 1B/O:8 were also isolated from two deer, and Y. pseudotuberculosis serogroups 3 and 4 were isolated from two boars and a deer, respectively. The pathogenic Y. enterocolitica 1B/O:8 isolates carried four virulence genes (ail, ystA, yadA, and virF), and Y. pseudotuberculosis serogroups 3 and 4 isolates carried three virulence genes (inv, yadA, and lcrF). Although the Y. enterocolitica 1B/O:8 and Y. pseudotuberculosis isolates were sensitive to almost all the antimicrobials tested, the two Y. enterocolitica 1B/O:8 isolates were resistant to azithromycin and ampicillin, and the three Y. pseudotuberculosis isolates were resistant only to azithromycin. These findings suggested that wild deer and boars might be important reservoirs for the agent causing human yersiniosis.