Primary Outcomes for Adults Receiving the Unified Protocol after Hurricane Harvey in an Integrated Healthcare Setting.
Primary Outcomes for Adults Receiving the Unified Protocol after Hurricane Harvey in an Integrated Healthcare Setting.
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DOI：
10.1007/s10597-022-00967-1
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发表时间：
2022-11
影响因子：
2.7
通讯作者：
Storch EA
中科院分区：
文献类型：
--
作者：
Weinzimmer SA;Goetz AR;Guzick AG;Hana LM;Cepeda SL;Schneider SC;Kennedy SM;Amos Nwankwo GN;Christian CC;Shaw AM;Salloum A;Shah AA;Goodman WK;Ehrenreich-May J;Storch EA
情绪障碍跨诊断治疗统一方案(UP)已证明对治疗焦虑和抑郁有效。然而，当在包括创伤患者在内的不同人群的现实世界环境中进行时，有效性数据有限。我们在一个自然主义的社区环境中评估了279名成人的治疗结果，这些成年人在飓风哈维之后接受了治疗。我们检查了总体临床严重性、抑郁和焦虑症状、功能障碍和基线结果预测因素的变化(即人口统计特征、飓风哈维的影响、抑郁和焦虑症状的共同出现)。全球临床严重程度、抑郁和焦虑症状以及功能障碍随着治疗结束而减少。参与者的整体症状改善程度低于疗效试验。经历了更大风暴影响的参与者报告说，与那些受哈维影响较小的参与者相比，焦虑症状的减少幅度更大。还需要用不同的样本进一步研究灾后评估UP的有效性。
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) has demonstrated efficacy for treating anxiety and depression. However, there are limited effectiveness data when conducted in real-world settings with diverse populations, including those with trauma. We evaluated treatment outcomes in a naturalistic, community setting among 279 adults who received UP following Hurricane Harvey. We examined change in overall clinical severity, depression and anxiety symptoms, functional impairment, and baseline outcome predictors (i.e., demographic characteristics, impact from Hurricane Harvey, co-occurrence of depression and anxiety symptoms). Global clinical severity, depression and anxiety symptoms, and functional impairment decreased by end-of-treatment. Participants experienced global symptom improvement to a lesser degree than demonstrated in efficacy trials. Participants who experienced greater storm impact reported larger reductions in anxiety symptoms than those less impacted by Harvey. Further studies evaluating the effectiveness of the UP post-disaster and with diverse samples are needed.