Spatial landscape of the tumor immune microenvironment.
Spatial landscape of the tumor immune microenvironment.
复制标题
肿瘤免疫微环境的空间景观。
DOI:
10.1016/j.trecan.2023.03.006
复制
发表时间:
2023
期刊:
影响因子:
18.4
通讯作者:
Han,Leng
中科院分区:
文献类型:
--
作者:
Chen,Yamei;Liu,Yuan;Han,Leng
Two recent studies published inNatureby Karimi et al. and Sorin et al. applied multiplexed imaging mass cytometry (IMC) to characterize the single-cell tumor immune landscapes covering millions of cells in brain tumors and lung adenocarcinomas (LUAD). They identified specific cell subtypes and cell–cell interactions that correlate with distinct clinical outcomes, thus providing valuable insights into tumor biology and prognostic prediction based on spatial architecture.