The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the dog
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the dog
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DOI：
10.1016/j.joca.2010.04.017
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发表时间：
2010-10-01
影响因子：
7
通讯作者：
Lafeber, F. P. J. G.
中科院分区：
文献类型：
--
作者：
Cook, J. L.;Kuroki, K.;Lafeber, F. P. J. G.
犬是研究骨关节炎（OA）的常用模型。主观组织学评分系统通常作为OA存在和严重程度的参考标准。然而，这些评分系统存在明显的缺点。本报告开发的系统试图通过提供一种标准化方法来解决这些缺点，该方法用于关节、通用性和病理学相对权重的整体评估，允许在时间点之间进行比较。研究、中心和系统可靠性的批判性分析拟议的犬组织评估系统似乎为OA关节病理学的全面评估提供了一种有效的方法该系统是通用的、全面的和可靠的，似乎比传统的评分系统具有优势（C）2010年国际骨关节炎研究协会由Elsevier Ltd.出版。版权所有
The dog is a common model for study of osteoarthritis (OA). Subjective histologic scoring systems have often served as the reference standard for presence and severity of OA However, these scoring systems have perceived shortcomings The system developed for this report attempts to address these shortcomings by providing a standardized methodology for global assessment of the joint, versatility and the potential for relative weighting of pathology, allowing for comparison among time points. studies, and centers, and critical analysis of the system's reliability The proposed system for assessment of canine tissues appears to provide an effective method for global assessment of articular pathology in OA The system is versatile, comprehensive, and reliable and appears to have advantages over conventional scoring systems (C) 2010 Osteoarthritis Research Society International Published by Elsevier Ltd. All rights reserved