Expression and plasticity of NO synthase in the neuroendocrine system
Expression and plasticity of NO synthase in the neuroendocrine system
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DOI：
10.1016/s0361-9230(97)00239-6
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发表时间：
1997-01-01
影响因子：
3.8
通讯作者：
Ceccatelli, S
中科院分区：
文献类型：
--
作者：
Ceccatelli, S
用原位杂交和免疫组织化学方法分析了一氧化氮合酶(NOS)在下丘脑多个核团和垂体中的表达，探讨了生理刺激和实验刺激对NOS表达的影响，并用原代培养的垂体细胞研究了NO在垂体前叶激素黄体生成素(LH)分泌中的作用，结果表明神经元型NOS的表达受激素调节，提示NO在激素分泌中起作用。(C)1997年爱思唯尔科学公司。
The expression of the nitric oxide (NO)-synthase enzyme (NOS) was analyzed in several hypothalamic nuclei and in the pituitary gland using in situ hybridization and immunohistochemistry, The effects of physiological and experimental stimuli on the expression of NOS was also investigated, Moreover, the role of NO in the secretion of anterior pituitary hormone luteinizing hormone (LH) was studied using primary culture of pituitary cells, The findings indicate that the expression of neuronal NOS is hormonally regulated and suggest that NO plays a role in hormone secretion. (C) 1997 Elsevier Science Inc.