The timing and laminar profile of converging inputs to multisensory areas of the macaque neocortex
The timing and laminar profile of converging inputs to multisensory areas of the macaque neocortex
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DOI：
10.1016/s0926-6410(02)00073-3
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发表时间：
2002-06-01
期刊：
影响因子：
--
通讯作者：
Foxe, JJ
中科院分区：
文献类型：
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作者：
Schroeder, CE;Foxe, JJ
多感觉整合的两个基本要求是不同感觉（如视觉和听觉）输入的收敛和对收敛输入的神经反应的时间对齐。本研究通过观察后听联合皮层、颞上多感觉区和腹侧顶叶内沟区这三个发生融合的区域，探讨了多感觉会聚的解剖机制。其中第一个区域最近被证明是多感觉融合的场所，后两个区域更被称为“经典”多感觉区域。在每种情况下，我们都着重于定义对无感觉输入的响应的层流剖面。这一信息是有用的，因为两种主要的连接类型，前馈和反馈，在层流终止模式上有特征差异，这在生理上表现出来。在相同的多感觉收敛区域，我们还检查了在所有记录中使用相同的标准化刺激的无感觉输入的时间。结果表明：(1)体感输入[J]。Neurophysiol。[j], 85(2001) 1322]，视觉输入在听觉处理的非常早期阶段可用，(2)收敛通过反馈发生，以及前馈解剖投影，(3)输入时间可能是一种资产，同时也是多感觉处理的约束。(C) 2002 Elsevier Science B.V.版权所有
Two fundamental requirements for multisensory integration are convergence of unisensory (e.g. visual and auditory) inputs and temporal alignment of the neural responses to convergent inputs. We investigated the anatomic mechanisms of multisensory convergence by examining three areas in which convergence occurs, posterior auditory association cortex, superior temporal polysensory area (STP) and ventral intraparietal sulcus area (VIP). The first of these was recently shown to be a site of multisensory convergence and the latter two are more well known as 'classic' multisensory regions. In each case, we focused on defining the laminar profile of response to the unisensory inputs. This information is useful because two major types of connection, feedforward and feedback, have characteristic differences in laminar termination patterns, which manifest physiologically. In the same multisensory convergence areas we also examined the timing of the unisensory inputs using the same standardized stimuli across all recordings. Our findings indicate that: (1) like somatosensory input [J. Neurophysiol., 85 (2001) 1322], visual input is available at very early stages of auditory processing, (2) convergence occurs through feedback, as well as feedforward anatomical projections and (3) input timing may be an asset, as well as a constraint in multisensory processing. (C) 2002 Elsevier Science B.V. All rights reserved.