A Database System for the Management and Karyotype Analysis of Chromosome Image Data
A Database System for the Management and Karyotype Analysis of Chromosome Image Data
复制标题
染色体图像数据管理和核型分析的数据库系统
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
K. Satou
中科院分区：
文献类型：
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作者：
Akihiro Kawaguchi;K. Satou
在许多生物学实验室中，大量的染色体图像数据的存储、检索和管理是非常重要的，这些实验室通常进行FISH和GISH实验。为此，保守的数据管理方式，即每个技术人员将他们的实验数据保存在自己的PC上，将破坏数千或数百万的图像数据。此外，在这些实验室中还需要图像数据的版本管理，因为核型分析意味着从由冷却的CCD相机拍摄的原始图像数据到最终图像数据的一系列图像处理，在最终图像数据中，所有染色体被裁剪、垂直定向并按其大小排序。为了帮助这样的染色体图像数据管理，我们正在开发一个数据库系统，用于存储，检索和核型分析（图1）。
In many laboratories of biology which usually doing FISH and GISH experiments, it is important to store, retrieve, and manage large amount of chromosome image data easily. For this purpose, conservative way of data management, that is, each technician keeps their experimental data in their own PCs, will ruin for thousands or millions of image data. Furthermore, version management of image data is also needed in such laboratories since karyotype analysis means a series of image processing from raw image data taken by cooled CCD camera to final image data in which all the chromosomes are cropped, directed vertically, and sorted in the order of their size. To assist such a chromosome image data management, we are developing a database system for storing, retrieval, and karyotype analysis of them (Fig. 1).