How Does Cross-Linking Affect the Stability of Block Copolymer Vesicles in the Presence of Surfactant?
How Does Cross-Linking Affect the Stability of Block Copolymer Vesicles in the Presence of Surfactant?
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DOI：
10.1021/la204539c
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发表时间：
2012-01-17
期刊：
影响因子：
3.9
通讯作者：
Armes, S. P.
中科院分区：
文献类型：
--
作者：
Chambon, P.;Blanazs, A.;Armes, S. P.
嵌段共聚物囊泡方便地通过聚合在水中以相对高的固体直接制备。使用基于甲基丙烯酸2-羟丙酯的水分散体聚合制剂诱导自组装。然而，动态光散射研究清楚地表明，添加小分子表面活性剂到这样的线性共聚物囊泡破坏囊泡膜。在离子型表面活性剂的情况下，这导致囊泡快速溶解，非离子型表面活性剂证明破坏性较小。为了解决这个问题，甲基丙烯酸缩水甘油酯可以与甲基丙烯酸2-羟丙酯共聚，并且所得的环氧官能嵌段共聚物囊泡容易在水溶液中使用廉价的市售聚合物二胺交联。这样的环氧-胺化学赋予特殊的表面活性剂耐受性的交联囊泡，也导致其形态的独特变化，通过透射电子显微镜判断。此外，未反应的胺基侧基赋予这些交联囊泡阳离子特性，并提供进一步的官能化机会。
Block copolymer vesicles are conveniently prepared directly in water at relatively high solids by polymerization. induced self-assembly using an aqueous dispersion polymerization formulation based on 2-hydroxypropyl methacrylate. However, dynamic light scattering studies clearly demonstrate that addition of small molecule surfactants to such linear copolymer vesicles disrupts the vesicular membrane. This causes rapid vesicle dissolution in the case of ionic surfactants, with nonionic surfactants proving somewhat less destructive. To address this problem, glycidyl methacrylate can be copolymerized with 2-hydroxypropyl methacrylate and the resulting epoxy-functional block copolymer vesicles are readily cross-linked in aqueous solution using cheap commercially available polymeric diamines. Such epoxy-amine chemistry confers exceptional surfactant tolerance on the cross-linked vesicles and also leads to a distinctive change in their morphology, as judged by transmission electron microscopy. Moreover, pendent unreacted amine groups confer cationic character on these cross-linked vesicles and offer further opportunities for functionalization.