LIQUID-CRYSTALS - A TOOL FOR STUDIES ON CHIRALITY
LIQUID-CRYSTALS - A TOOL FOR STUDIES ON CHIRALITY
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DOI：
10.1002/anie.198403481
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发表时间：
1984-01-01
影响因子：
16.6
通讯作者：
ZIMMERMANN, RG
中科院分区：
文献类型：
--
作者：
SOLLADIE, G;ZIMMERMANN, RG
向列型液晶对光学活性分子非常敏感，在非常低的浓度下，这些分子会转化为胆甾型液晶。本文综述了近年来液晶在手性研究中的应用。简要讨论了液晶的结构和性质，然后概述了目前用于测定胆甾型液晶的节距和手性的方法。对诱导胆甾相的形成特别感兴趣的是光学活性化合物的扭转力以及掺杂剂和向列相之间的结构关系。除其他外，液晶可用于小光学活性的检测和热消旋势垒和绝对构型的测定。
Nematic liquid crystals are extremely sensitive to optically active molecules, which, at very low concentration, convert them into cholesteric liquid crystals. The purpose of this report is to review recent applications of liquid crystals to chirality studies. A brief discussion of the structure and properties of liquid crystals is followed by a survey of the methods currently being employed for the determination of the pitch and handedness of cholesteric liquid crystals. Of special interest in the formation of induced‐cholestric phases are the twisting powers of optically active compounds and the structural relationships between dopants and nematics. Liquid crystals can be used, inter alia, for the detection of small optical activities and for the determination of thermal racemization barriers and absolute configurations.