Is there evidence for symptoms of cannabis withdrawal in the national epidemiologic survey of alcohol and related conditions?
Is there evidence for symptoms of cannabis withdrawal in the national epidemiologic survey of alcohol and related conditions?
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DOI：
10.1080/10550490802019519
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发表时间：
2008-05-01
影响因子：
3.7
通讯作者：
Lynskey, Michael T.
中科院分区：
文献类型：
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作者：
Agrawal, Arpana;Pergadia, Michele L.;Lynskey, Michael T.
我们研究了美国普通人群中20种大麻戒断症状的患病率。在过去12个月的大麻使用者中，超过29%的人报告至少经历过两次大麻戒断症状，8%的人报告至少有两次症状或戒断症状。最常见的戒断症状是吃得比平时多/体重增加。与其他非法药物使用情况一样，同时使用烟草略微增加了报告某些症状的可能性，尽管程度较低。即使在控制了大麻使用的强度之后，父母酒精/药物问题的历史也与经历大麻戒断的可能性增加有关。从这个和以前的研究表明退出的证据强烈表明，DSM的未来版本需要重新考虑从大麻依赖的标准中排除退出。
We examined the prevalence of 20 individual symptoms of cannabis withdrawal in the U.S. general population. More than 29% of past 12-month cannabis users reported experiencing at least two cannabis withdrawal symptoms, with 8% reporting impairment from at least two symptoms or withdrawal relief. The most common withdrawal symptom was eating more than usual/gaining weight. Co-occurring tobacco use modestly increased the likelihood of reporting certain symptoms, as did other illicit drug use, though to a lesser degree. Even after controlling for intensity of cannabis use, a history of parental alcohol/drug problems was associated with an increased likelihood of experiencing cannabis withdrawal. Evidence from this and prior studies demonstrating withdrawal strongly suggest that future editions of DSM need to reconsider the exclusion of withdrawal from criteria for cannabis dependence.