Histology of the transverse carpal ligament and flexor tenosynovium in idiopathic carpal tunnel syndrome

Histology of the transverse carpal ligament and flexor tenosynovium in idiopathic carpal tunnel syndrome
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DOI:
10.1016/s0363-5023(98)80009-9
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发表时间:
1998-11-01
影响因子:
1.9
通讯作者:
Tachibana, S
Tachibana, S
中科院分区:
医学3区
文献类型:
--
作者:
Nakamichi, K;Tachibana, S

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对130例特发性腕管综合征患者的166个腕关节进行腕横韧带和屈肌腱滑膜的组织学研究。来自9个对照的9个手腕用于比较。73.5%的韧带和56.0%的肌腱滑膜组织学正常。在其余标本中,韧带显示粘液样改变(17.5%)、淀粉样沉积(7.8%)、炎症(3.0%)和软骨化生(2.4%),肌腱滑膜显示纤维化(25.3%)、水肿(7.2%)、炎症(10.2%)、淀粉样沉积(8.4%)和血管肥大(4.8%)。大多数这些变化的程度为轻度,病理生理学似乎无意义。我们的结论是,在特发性腕管综合征,韧带和腱鞘往往表现出正常的组织学,并没有典型的或一致的变化,特发性腕管综合征可以与。(J Hand Surg 1998;23A:1015-1024.版权所有(C)1998美国手外科学会。
Histology of the transverse carpal ligament and flexor tenosynovium was investigated in 166 wrists from 130 patients with idiopathic carpal tunnel syndrome. Nine wrists from 9 controls were used for comparison. In the patients, 73.5% of the ligament and 56.0% of the tenosynovium showed normal histology. In the remaining specimens, the ligament showed mucoid change (17.5%), amyloid deposits (7.8%), inflammation (3.0%), and chondrometaplasia (2.4%), and the tenosynovium showed fibrosis (25.3%), edema (7.2%), inflammation (10.2%), amyloid deposits (8.4%), and vascular hypertrophy (4.8%). The majority of these changes were mild in degree and the pathophysiology did not appear to be meaningful. We conclude that in idiopathic carpal tunnel syndrome, the ligament and tenosynovium often show normal histology and there are no typical or consistent changes with which idiopathic carpal tunnel syndrome can be associated. (J Hand Surg 1998;23A:1015-1024. Copyright (C) 1998 by the American Society for Surgery of the Hand.).