Epidemiological Analysis of Venous Malformation of the Orbit
Epidemiological Analysis of Venous Malformation of the Orbit
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DOI：
10.1097/scs.0000000000006095
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发表时间：
2020-05-01
影响因子：
0.9
通讯作者：
Bonavolonta, Giulio
中科院分区：
文献类型：
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作者：
Bonavolonta, Paola;Fossataro, Federica;Bonavolonta, Giulio
眼眶静脉畸形（OVM）是成人最常见的眼眶肿块之一，约占中枢神经系统所有血管异常的5%至15%，占眼眶病变的9%。临床表现从无症状病例到有症状病例是可变的。作者工作的目的是分析在过去40年中转诊到眼眶病三级中心眼眶科的患者队列中OVM的发病率和患病率。回顾性审查了40年期间诊断为CVM的224例患者的记录，根据从欧盟统计局人口统计数据提取患病率/年和发病率/年。使用Microsoft Excel（Microsoft Corporation，雷德蒙，华盛顿州）电子数据表汇总和分析数据。发病率以在三级中心Orbital Unit观察到的OVM新发病例数衡量。发病率约为每1000万人1例（0.94）。发病率也以在坎帕尼亚观察到的OVM新发病例数来衡量，考虑到后一种情况下该地区的患者居民（112例患者）。发病率低于每1000万人1例（0.58）。患病率是以我们的轨道单位观察到的OVM个体的比例来衡量的，等于5%。这一指标从1977年到2017年有所增加。OVM的治疗仍在讨论中，但与文献中的数据一致，作者仍然认为手术适应症仅适用于症状性病变。
Orbital venous malformation (OVM) is one of the most common orbital mass of adults, accounting for approximately 5% to 15% of all vascular abnormalities in the central nervous system and representing 9% of orbital lesions. Clinical presentation is variable from asymptomatic cases to symptomatic ones. The purpose of the authors' work is to analyze OVM incidence and prevalence in a cohort of patients referred over the last 40 years to the Orbital Unit, tertiary center for orbital diseases. Records of 224 patients diagnosed with CVM in a 40-year period were retrospectively reviewed extracting prevalence/year and incidence/year based on data obtained from Eurostat population statistics. Data were aggregate and analyzed with a Microsoft Excel (Microsoft Corporation, Redmond, WA) spread sheet. The incidence rate was measured as the number of new cases of OVM observed in Orbital Unit, a tertiary center. Incidence was about 1 case out (0.94) every 10 million people. The incidence rate was measured also as the number of new cases of OVM observed in Campania, considering in the latter case patients residents in this region (112 patients). Incidence was less than 1 case out (0.58) every 10 million people. The prevalence rate was measured as the proportion of individuals with OVM observed in our Orbital Unit and is equal to 5%. This indicator resulted to increase from 1977 to 2017. The management of OVM is still under discussion, but in agreement with data present in the literature the authors still believe that the surgical indication is only for symptomatic lesions.