THE RELATIONSHIP BETWEEN COLONIZATION, SECRETOR STATUS AND INVITRO ADHESION OF CANDIDA-ALBICANS TO BUCCAL EPITHELIAL-CELLS FROM DIABETICS
THE RELATIONSHIP BETWEEN COLONIZATION, SECRETOR STATUS AND INVITRO ADHESION OF CANDIDA-ALBICANS TO BUCCAL EPITHELIAL-CELLS FROM DIABETICS
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DOI：
10.1099/00222615-33-1-43
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发表时间：
1990-09-01
影响因子：
3
通讯作者：
MACCUISH, AC
中科院分区：
文献类型：
--
作者：
DARWAZEH, AMG;LAMEY, PJ;MACCUISH, AC
本研究旨在探讨糖尿病患者口腔念珠菌感染与体外培养白色念珠菌粘附口腔上皮细胞是否相关。与50名年龄、性别和假牙状况相匹配的非糖尿病对照组相比，来自50名糖尿病患者的口腔细胞显示白色念珠菌菌株cd88的粘附性显著增加。观察两组口腔念珠菌携带情况、感染情况及分泌物情况。携带念珠菌的频率增加，但不明显，糖尿病患者的念珠菌感染发生率明显高于对照组。非分泌型糖尿病患者口腔念珠菌携带的频率显著增加。
This study investigated whether oral Candida infection in diabetics and adhesion of Candida albicans to buccal epithelial cells in vitro were related. Buccal cells from 50 patients with diabetes mellitus showed a significant increase in adhesion of C. albicans strain CDS 88 compared with those collected from 50 non-diabetic controls matched for age, sex and denture status. Oral Candida carriage, Candida infection and secretor status were also investigated in both groups. The frequency of carriage was increased, but not significantly, and there was a significantly higher incidence of Candida infection in diabetic patients compared with controls. Diabetic patients who were non-secretors had a significantly increased frequency of oral Candida carriage.