Association between weight gain, obesity, and sleep duration: a large-scale 3-year cohort study
Association between weight gain, obesity, and sleep duration: a large-scale 3-year cohort study
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DOI：
10.1007/s11325-011-0583-0
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发表时间：
2012-09-01
影响因子：
2.5
通讯作者：
Fukui, Tsuguya
中科院分区：
文献类型：
--
作者：
Kobayashi, Daiki;Takahashi, Osamu;Fukui, Tsuguya
先前的研究表明，睡眠时间与肥胖和体重增加有关。然而，这些研究大多是横断面设计，只有少数队列研究。为了在更真实的环境中验证之前的发现，我们在一项为期3年的大型队列研究中评估了睡眠时间、肥胖和体重增加之间的关系。2005年至2008年期间，在圣卢克国际医院预防医学中心进行了一项回顾性队列研究，涉及21,469名年龄在20岁或以上的健康个体，他们每年都接受健康检查。参与者根据他们自己报告的平均夜间睡眠时间（每千分之一货币符号5、6、7和每千分之一日元8小时）被分为四组。我们确定了肥胖（体重指数为千分之一日元25 kg/m(2)）和体重增加的个体。采用多变量线性回归分析和logistic回归分析来探讨这些变量与睡眠时间之间的关系，并对年龄、性别、饮酒、当前吸烟、既往病史和体育活动水平进行调整。与睡7小时的人相比，每晚睡5小时的人更有可能出现体重增加（β系数= 0.03;95% CI = 0.03-1.1）和肥胖（OR = 1.5; 95% CI = 1.1-2.0）。睡眠时间超过8小时的受试者与睡眠时间为7小时的受试者之间无显著差异（OR = 1.3; 95% CI = 0.9-1.8）。无论是男性还是女性，睡眠不足（千分之一小时）都与体重增加和肥胖密切相关。
Previous research suggests that sleep duration is associated with obesity and weight gain. However, the majority of these studies are of cross-sectional design, with only a few cohort studies. In order to validate previous findings in a more real-world context, we evaluated the association between sleep duration, obesity, and weight gain in a large, 3-year cohort study.A retrospective cohort study was conducted involving 21,469 apparently healthy individuals aged 20 years or older who underwent annual health check-ups at the Center for Preventive Medicine, St. Luke's International Hospital, between 2005 and 2008. The participants were divided into four groups according to their self-reported average nightly sleep duration (a parts per thousand currency sign5, 6, 7, and a parts per thousand yen8 h). We identified individuals with obesity (body mass index a parts per thousand yen25 kg/m(2)) and weight gain. Multivariate linear regression analysis and logistic regression analysis were used to explore the association between these variables and sleep duration, adjusting for age, gender, alcohol consumption, current smoking, past medical history, and level of physical activity.Compared with those who slept 7 h, the individuals who slept a parts per thousand currency sign5 h night were more likely to experience weight gain (beta coefficient = 0.03; 95% CI = 0.03-1.1) and to become obese (OR = 1.5; 95% CI = 1.1-2.0). No significant difference was seen between subjects who slept more than 8 h and those sleeping 7 h (OR = 1.3; 95% CI = 0.9-1.8).Short sleep (a parts per thousand currency sign5 h) is significantly associated with weight gain and obesity in both male and female adults.