Reactive Cells and Their Role in Glial Regeneration in an Insect CNS
Reactive Cells and Their Role in Glial Regeneration in an Insect CNS
复制标题
反应细胞及其在昆虫中枢神经系统神经胶质再生中的作用
DOI：
10.1093/icb/28.4.1145
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发表时间：
1988
影响因子：
2.6
通讯作者：
J. Treherne
中科院分区：
文献类型：
--
作者：
Peter J. S. Smith;E. Howes;J. Treherne
概要。蟑螂中枢神经连接中的选择性 Ghal 破坏会导致快速且有组织的修复，其与脊椎动物大脑中的等效过程具有许多特征，特别是来自循环血细胞的外源反应细胞的关键参与。这些细胞在修复的最初几天内大量出现在受损组织中，在结构上对海藻再生非常重要。他们还协调内源性反应细胞的招募和组织。侵袭性细胞转化为功能性神经元或被功能性神经元取代，与神经周围血脑屏障的恢复和细胞分裂的开始同时发生。
SYNOPSIS. Selective ghal disruption in cockroach central nervous connectives results in a swift and organized repair which shares a number of features with the equivalent processes in the vertebrate brain notably, a critical involvement of exogenous reactive cells derived from circulating haemocytes. These cells, which appear in the lesioned tissues in large numbers during the first few days of repair, are structurally important in ghal regeneration. They also orchestrate the recruitment and organisation of endogenous reactive cells. The invasive cells transform into, or are replaced by, functional neurogha, coincident with the restoration of the perineunal blood–brain barrier and the onset of cell division.