A randomized trial of the effect of single-vision vs. bifocal lenses on myopia progression in children with esophoria
A randomized trial of the effect of single-vision vs. bifocal lenses on myopia progression in children with esophoria
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DOI：
10.1097/00006324-200008000-00006
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发表时间：
2000-08-01
影响因子：
1.4
通讯作者：
Parker, DE
中科院分区：
文献类型：
--
作者：
Fulk, GW;Cyert, LA;Parker, DE
背景资料：长期以来，双焦点被认为可以减少儿童近视的进展，然而，这一假设尚未得到明确的评估，方法：我们进行了一项随机临床试验，以检验双光眼镜减缓近点近视儿童近视进展的假设，82名近视儿童被随机分配到单光眼镜组（n = 40）或具有+1.50 D附加值的双光眼镜组（n = 42），并随访30个月。在睫状肌麻痹后通过自动验光仪测量屈光度，主要结果是近视进展，定义为基线和30个月检查时的等效球镜之间的差异，双眼平均值。结果如下：双焦点组中有6名儿童和单焦点组中有1名儿童的随访不完整，在完成30个月随访的儿童中，（双眼的平均等效球镜），双焦点平均为0.99 D，单焦点平均为1.24 D（未调整，p = 0.106;经年龄校正，p = 0.046），治疗组的累积分布不同（Kolmogorov-Smirnov程序，p = 0.031），对玻璃体腔深度生长的治疗效果的证据相似（K.S.的p = 0.046），结论：使用双光眼镜，而不是单视觉草，近点近视的儿童似乎减缓近视进展到轻微的程度。
Background: Bifocals have long been thought to reduce progression of childhood myopia, However, this hypothesis has not been definitively evaluated, Methods: We conducted a randomized clinical trial to test the hypothesis that bifocals slow myopia progression in children with near-point esophoria, Eighty-two myopic children were randomized to single-vision glasses (n = 40) or to bifocals with a +1.50 D add (n = 42) and were followed for 30 months. Refraction was measured by an automated refractor after cycloplegia, The primary outcome was myopia progression defined as the difference between the spherical equivalent at baseline and at the 30-month examination, averaged over both eyes. Results: Follow-up was incomplete for six children in the bifocal group and one child in the single-vision group, Among the children completing the 30 months of follow up, myopia progression (mean spherical equivalent of the two eyes) averaged 0.99 D for bifocals and 1.24 D for single vision (unadjusted, p = 0.106; adjusted for age, p = 0.046), Treatment groups differed in their cumulative distributions (Kolmogorov-Smirnov procedure, p = 0.031), Evidence for a treatment effect on growth in vitreous chamber depth was similar (p = 0.046 by K.S.), Conclusion: Use of bifocals, instead of single-vision grasses, by children with near-point esophoria seemed to slow myopia progression to a slight degree.