Time-lapse analysis of retinal differentiation.
Time-lapse analysis of retinal differentiation.
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DOI：
10.1016/j.ceb.2005.09.004
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发表时间：
2005-12
影响因子：
7.5
通讯作者：
L. Poggi;F. R. Zolessi;W. Harris
中科院分区：
文献类型：
--
作者：
L. Poggi;F. R. Zolessi;W. Harris
新的重要标志物的可用性和延时视频显微镜的改进增加了我们观察视网膜发育事件的能力。使用这种方法，在理解重要问题方面取得了进展，例如分裂模式如何与细胞命运决定相关，有丝分裂后祖细胞如何到达正确的视网膜层，以及最后，视网膜神经节细胞轴突如何导航出视网膜并到达中脑中的最终目标。
The availability of new vital markers and the improvements in time-lapse video microscopy have increased our ability to observe developmental events in the retina while they are happening. Using this approach, advances have been made in the understanding of important issues such as how division patterns relate to cell fate determination, how post-mitotic progenitors reach their correct retinal layers, and finally, how retinal ganglion cell axons navigate out of the retina and to their final targets in the midbrain.