Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion
Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion
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DOI：
10.1111/bjh.14383
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发表时间：
2017-01-01
影响因子：
6.5
通讯作者：
Ryan, Kate
中科院分区：
文献类型：
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作者：
Davis, Bernard A.;Allard, Shubha;Ryan, Kate
在急诊和非急诊环境中，红细胞输注在镰状细胞病(SCD)的治疗中起着重要的作用。然而，由于随机数据不足，何时或如何使用红细胞输注并不总是很清楚。配套指南《镰状细胞病红细胞输注指南第一部分：原则和实验室方面》阐述了SCD输血实践的一般原则(Davis等人，2016，BJH在出版中)。本指南审查了目前关于SCD输血适应症的现有证据。这可能并不适合所有的临床方案，临床决策必须基于个别患者的考虑。在这两个指南中，术语镰状细胞病是指疾病的所有基因类型，镰状细胞性贫血是指纯合子状态(SS)。
Red cell transfusion has an important role in the management of sickle cell disease (SCD) in both emergency and elective settings. However, because of insufficient randomised data, it is not always clear when or how to use red cell transfusion. A companion guideline, Guidelines on red cell transfusion in sickle cell disease Part I: principles and laboratory aspects, addresses the general principles of transfusion practice in SCD (Davis et al, 2016, BJH in press). The present guideline examines current available evidence on indications for transfusion in SCD. This may not be appropriate for all clinical scenarios and clinical decisions must be based on individual patient considerations. In both guidelines, the term sickle cell disease refers to all genotypes of the disease, and sickle cell anaemia to the homozygous state (SS).