A Short Enantioselective Total Synthesis of the Fundamental Pentacyclic Triterpene Lupeol
A Short Enantioselective Total Synthesis of the Fundamental Pentacyclic Triterpene Lupeol
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DOI：
10.1021/ja906335u
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发表时间：
2009-10-07
影响因子：
15
通讯作者：
Corey, E. J.
中科院分区：
文献类型：
--
作者：
Surendra, Karavadhi;Corey, E. J.
The first enantioselective synthesis of lupeol has been developed by applying two carefully crafted cation-pi cyclization stages to generate the pentacyclic structure with complete stereocontrol. The synthesis (Scheme 1) is noteworthy because of its brevity and also because it solves a longstanding problem in the field of natural product synthesis.
