Increased incidence of depressive symptoms in men with erectile dysfunction
Increased incidence of depressive symptoms in men with erectile dysfunction
复制标题
DOI：
10.1016/s0090-4295(98)00292-1
复制
发表时间：
1998-11-01
期刊：
影响因子：
2.1
通讯作者：
Ritter, JS
中科院分区：
文献类型：
--
作者：
Shabsigh, R;Klein, LT;Ritter, JS
目标.研究勃起功能障碍（艾德）男性与年龄匹配的对照组相比抑郁症状发生率更高的假设。我们还假设抑郁症状影响性欲水平和ED治疗的成功。120例艾德和良性前列腺增生（BPH）患者分为三组。第1组仅患有艾德，第2组仅患有BPH，第3组同时患有艾德和BPH。使用精神障碍初级保健评估和贝克抑郁量表对患者进行抑郁症状筛查。他们还调查了合并症、婚姻状况、艾德的严重程度、性欲水平、以前的艾德治疗选择（如果有的话）、治疗成功率等。100名患者完成了问卷调查。48例单纯艾德患者中有26例（54%）报告有抑郁症状，18例艾德合并BPH患者中有10例（56%）报告有抑郁症状，34例单纯BPH患者中有7例（21%）报告有抑郁症状。艾德患者报告抑郁症状的可能性是单纯BPH患者的2.6倍（P < 0.005）。有抑郁症状的患者性欲较低（P < 0.0001）。三组间合并症的严重程度无差异。共有33例艾德患者既往接受过阴茎注射或真空装置治疗艾德。艾德组15例（100%）仅继续治疗并对疗效满意，而艾德组18例（38.9%）伴抑郁症状者仅7例（38.9%）继续治疗（P < 0.00021）。艾德与抑郁症状的高发生率相关，与年龄、婚姻状况或合并症无关。与对照组相比，艾德患者性欲下降。此外，有抑郁症状的患者比没有抑郁症状的患者性欲更低。与其他ED患者相比，艾德和抑郁症状的患者更有可能停止治疗艾德。这些数据强调了多学科方法治疗勃起功能障碍的重要性。(C)1998年，Elsevier Science Inc. All rights reserved.
Objectives. To investigate the hypothesis that men with erectile dysfunction (ED) have a higher incidence of depressive symptoms compared with age-matched control subjects. We also hypothesized that depressive symptoms impact on the level of libido and on the success of treatment of ED.Methods. One hundred twenty men with ED or benign prostatic hyperplasia (BPH) were divided into three groups. Group 1 had ED only, group 2 had BPH only, and group 3 had both ED and BPH. Patients were screened for depressive symptoms using the Primary Care Evaluation of Mental Disorders and the Beck Depression Inventory. They were also surveyed for comorbidity, marital status, severity of ED, level of libido, prior ED treatment choice (if any), success of treatment, and others.Results. One hundred patients completed the questionnaires. Depressive symptoms were reported by 26 (54%) of 48 men with ED alone, 10 (56%) of 18 men with ED and BPH, and 7 (21%) of 34 men with BPH alone. Patients with ED were 2.6 times more likely to report depressive symptoms than men with BPH alone (P < 0.005). Patients with depressive symptoms reported lower libido than other patients (P < 0.0001). Severity of comorbidities did not differ among the three groups. A total of 33 patients with ED had prior treatment for ED using penile injections or vacuum devices. AII 15 (100%) patients with ED only continued treatment and were satisfied with its outcome, whereas only 7 (38.9%) of 18 patients with ED and depressive symptoms continued treatment (P < 0.00021).Conclusions. ED is associated with high incidence of depressive symptoms, regardless of age, marital status, or comorbidities. Patients with ED have a decreased libido compared with control subjects. In addition, patients with depressive symptoms have a lower libido than patients without depressive symptoms. Patients with ED and depressive symptoms are more likely to discontinue treatment for ED than other patients with ED. These data emphasize the importance of a multidisciplinary approach to the treatment of erectile dysfunction. (C) 1998, Elsevier Science Inc. All rights reserved.