Correlates of lateral ventricular size in chronic schizophrenia, I: Behavioral and treatment response measures.
Correlates of lateral ventricular size in chronic schizophrenia, I: Behavioral and treatment response measures.
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慢性精神分裂症侧脑室大小的相关性，I：行为和治疗反应措施。
DOI：
10.1176/ajp.143.8.976
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
K. Davis
中科院分区：
文献类型：
--
作者：
M. Losonczy;I. S. Song;R. Mohs;N. A. Small;M. Davidson;C. Johns;K. Davis
28例男性无药物精神分裂症住院患者的脑室脑比（VBR）显著高于21例匹配的正常对照，且与阳性或阴性症状的严重程度无关。在一项使用固定剂量计划的6周开放试验中，氟哌啶醇的反应不是通过阳性或阴性症状的严重程度或VBR来预测的。9例严重恶化的慢性“Kraepelinian”型精神分裂症患者左侧脑室比右侧脑室大28%，而对照组和其他精神分裂症患者未出现心室不对称。
The ventricle-brain ratio (VBR) of 28 drug-free male schizophrenic inpatients was significantly higher than that of 21 matched normal control subjects and was not related to severity of positive or negative symptoms. Response to haloperidol in an open 6-week trial using a fixed-dose schedule was not predicted by severity of positive or negative symptoms or by VBR. The nine severely deteriorated patients with chronic "Kraepelinian" schizophrenia had left lateral ventricles 28% larger than their right, whereas the control subjects and other schizophrenic patients did not show ventricular asymmetry.