Fear extinction in rodents.
Fear extinction in rodents.
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DOI：
10.1002/0471142301.ns0823s47
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发表时间：
2009-04
影响因子：
--
通讯作者：
Maren, Stephen
中科院分区：
文献类型：
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作者：
Chang, Chun-hui;Knapska, Ewelina;Orsini, Caitlin A;Rabinak, Christine A;Zimmerman, Joshua M;Maren, Stephen
巴甫洛夫条件反射范式已经成为理解行为神经科学的重要模型系统。特别是，关于巴甫洛夫恐惧反应消失的研究正在产生关于人类焦虑症的神经基础的重要信息。这些研究与理解抑制恐惧的行为干预背后的神经机制密切相关，包括暴露疗法。本章描述了检查实验室啮齿动物恐惧消退的性质和特性的详细行为规程。
Pavlovian conditioning paradigms have become important model systems for understanding the neuroscience of behavior. In particular, studies of the extinction of Pavlovian fear responses are yielding important information about the neural substrates of anxiety disorders in humans. These studies are germane to understanding the neural mechanisms underlying behavioral interventions that suppress fear, including exposure therapy. This chapter described detailed behavioral protocols for examining the nature and properties of fear extinction in laboratory rodents.